Teachntest 
Adverse drug reactions (ADR) are important causes of deaths and hospitalization worldwide. ADR affects the patient’s compliance to treatments and may affect their trust in healthcare system. India has developed a platform for ADR monitoring & reporting since 1982, but despite of having wide population, the reporting rate of ADR’s is nowhere near to other small European countries.
The major electrolytes found in the human body are: Interstitial fluid and blood plasma are similar in their electrolyte make up. Na+ and Cl- being the major electrolytes. In the intracellular fluid, K+ and HPO4- are the major electrolytes.
Limit tests for chlorides, sulphates, lead, iron, heavy metals and arsenic are official tests designed and mentioned in the individual monograph of pharmaceutical substances in Indian Pharmacopoeia. The limit of impurity is provided in terms of parts per million(ppm).
Contents
Definition of Limit tests
Importance of Limit tests
Limit tests for Chloride- Principle, Procedure, Observation, Reasons
Limit tests for Sulphate – Principle, Procedure, Observation, Reasons
Limit tests for Iron – Principle, Procedure, Observation, Reasons
Limit tests for Heavy Metals – Principle, Procedure, Observation, Reasons
Limit tests for Arsenic – Principle, Procedure, Observation, Reasons
Limit test for chlorides, sulphates, lead, iron, heavy metals and arsenic are official tests designed and mentioned in the individual monograph of pharmaceutical substance in Indian Pharmacopoeia. The limit of impurity is provided in terms of parts per million(ppm).
Modern Dispensing Aspects MCQ’s: The goals of therapy will not be achieved unless the patient ‘-‘understands and follows the instructions for use of the drugs prescribed. The pharmacist is the logical health profession to assume the major responsibility in minimizing noncompliance. Of priority, importance is the need to strengthen communications with patients and physicians.
Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles. Size reduction process is also termed as comminution or diminution or pulverization. Normally, size reduction may be achieved by two methods, namely precipitation or mechanical process. In the precipitation method, the substance is dissolved in an appropriate solvent. This method is suitable for the production of raw materials and bulk drugs. Inorganic chemicals, such as calcium carbon ate, magnesium carbonate, and yellow mercuric oxide, are prepared by precipitation method. In the mechanical process, the substance is subjected to mechanical forces using grinding equipment (ball mill, roller mill, colloid mill, etc.).
