Displacement value in suppositories

The Fundamental Problem: Density Mismatch Imagine a suppository mould is like a fixed-volume ice cube tray. When you pour water in, each “cube” holds exactly 1 gram. The mould is calibrated for a specific volume. Now, the suppository base (e.g., cocoa butter) has a known density. The manufacturer calibrates the mould so that when you use pure base, the resulting suppository … Read more

Size Reduction MCQ’s

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Size Reduction

Prepared By: Ms. Twinkle A. Chaudhari and Mr. Sachin R. Gadhari

Size reduction is a process of reducing large solid unit masses into small unit masses, coarse particles or fine particles. Size reduction process is also termed as comminution or diminution or pulverization. Normally, size reduction may be achieved by two methods, namely precipitation or mechanical process. In the precipitation method, the substance is dissolved in an appropriate solvent. This method is suitable for the production of raw materials and bulk drugs. Inorganic chemicals, such as calcium carbon ate, magnesium carbonate, and yellow mercuric oxide, are prepared by precipitation method. In the mechanical process, the substance is subjected to mechanical forces using grinding equipment (ball mill, roller mill, colloid mill, etc.).

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